Propolis is the resinous mixture that honey bees gather from the sap of trees which contains a diverse array of bioflavonoids that varies depending on its geographic location.

New Zealand propolis is known to be very high in CAPE (caffeic acid phenethyl ester), a compound being studied around the world for a number of medical conditions. New research is published regularly, some of which is included below.

Antiproliferative activity of BIO30™ New Zealand Propolis and components vs Human colorectal adenocarcinoma cells

Propolis has been used by humans since antiquity for treating diseases. It is well known anecdotally and through in vitro bioassay for its antimicrobial, antioxidant, anti-inflammatory and more recently, anti-proliferative activity. Propolis use for health and wellness applications by oral ingestion has been limited due to lack of clinical data1, and apparently low absorption into the blood2,3. However, low absorption implies that the bioactives could benefit gastro-intestinal health. In this work we present results of a bioactivity-guided fractionation study of BIO30™ New Zealand Propolis, using DLD-1 colon adenocarcinoma cells and LPS-induced inflammation in neutrophils as a first indication of beneficial gastrointestinal health potential. Read more